Dr. Sebastian Lickert
Dr. Sebastian Lickert
Lecturer at the Department of Health Sciences and Technology
I have a background in micro-engineering and biology and my research is focusing on the mechano-regulation of blood cells with the ultimate goal to translate these observations into clinical practice.
Together with my team and collaborators we are currently developing a fundamentally new technology, where physical T cell activation by nanopores augments biochemical T cell stimulation. This novel strategy is based on our recent discovery (external pagePNAS 2021) that T cells sense and get stimulated by physical constraints. This is in stark contrast to all conventional activation methods used by the research community and all companies in this domain, where biochemical stimulation is necessary to activate T cells. It has the potential to improve the ex vivo production of T cells and to address unmet needs in cancer immunotherapies.
Also visit the website of my close external collaborator external pageProf. Dr. Enrico Klotzsch.
Main research tools:
- Optical Microscopy (CLSM, STORM, SIM, STED, LLSM)
- Molecular Biology (Western Blotting, Flow Cytometry, ELISA, Viral transduction)
- Microtechnology (μ-Lithography, -Fluidics, -Contact-Printing)
- Material Characterization and Optimization (FTIR, XPS, AFM, DRIE)
Are you interested?
I am always happy to supervise semester-, bachelor- or master-students. Don’t hesitate to contact me, and I will explain you my research in more detail.
Short CV:
Since 04/2022
Group Lead and entrepreneur at the Institute of Translational Medicine, Prof. Dr. Dr. hc. Viola Vogel, ETH Zurich, Switzerland
02/2020 – 03/2022
Lecturer and project leader at the Institute of Translational Medicine, Prof. Dr. Dr. hc. Viola Vogel, ETH Zurich, Switzerland
05/2015 – 02/2020
PhD candidate at the Institute of Translational Medicine, Prof. Dr. Dr. hc. Viola Vogel, ETH Zurich, Switzerland
10/2011 - 12/2014
Master degree in Microsystems Engineering, University of Freiburg, Germany
